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For example, administration of 2.4 mg/week of semaglutide (instead of 1 mg used in diabetics) for 68 weeks leads to average losses of 15% of initial body weight, approximately double that in type 2 diabetics (Figure 5A)
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Ciclo de Prctica I
Consequently, researchers have devoted decades to studying incretins, postulating that incretin-based therapies could potentially reverse this diminished incretin effect and restore insulin secretion in patients with T2DM
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