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The largest dataset based on whole-body counting is provided by Heinrich (Heinrich, 1967), who studied doses up to 100,000 g

Reduction of a trisulfide derivative of glutathione by glutathione reductase [PMID: 8060317] Laboratory literature summary: Reduction of a trisulfide derivative of glutathione by glutathione reductase

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The combination of this particular class with thiazolidinediones presents an interesting concept, currently under trial in a phase-4, open-label study, where empagliflozin is being evaluated alone and in conjunction with pioglitazone on diabetic patients, with the primary outcome being the measurement of liver fat content by MRI-PDFF (NCT03646292)