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[1] [3] Diagnosis [edit | edit source] Graves disease fi present clinically plus one anaa more of dese characteristic signs: Rapid heartbeat (80%) Diffuse palpable goiter plus audible bruit (70%) Tremor (40%) Exophthalmos (protuberance of one anaa both eyes), periorbital edema (25%) Fatigue (70%), weight loss (60%) plus increased appetite insyd young people den poor appetite insyd de elderly, den oda symptoms of hyperthyroidism/thyrotoxicosis Heat intolerance (55%) Tremulousness (55%) Palpitations (50%) Eye disease [edit | edit source] Severity of eye disease fi be classified by de mnemonic: "NO SPECS": [4] Class 0: No signs anaa symptoms Class 1: Only signs (limited to upper lid retraction den stare, plus anaa widout lid lag) Class 2: Soft tissue involvement (oedema of conjunctivae den lids, conjunctival injection, etc.) Class 3: Proptosis Class 4: Extraocular muscle involvement (usually plus diplopia) Class 5: Corneal involvement (primarily due to lagophthalmos) Class 6: Sight loss (due to optic nerve involvement) Antithyroid drugs [edit | edit source] Radioiodine [edit | edit source] Surgery [edit | edit source] Eyes [edit | edit source] Prognosis [edit | edit source] Epidemiology [edit | edit source] History [edit | edit source] Society den culture [edit | edit source] Notable cases [edit | edit source] Ayaka, Japanese singer, na dem diagnose plus Graves disease insyd 2007

Adems, se menciona el blanqueamiento cutneo como otro beneficio notable del producto

An activation of caspases was also detected (Fig