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Researchers utilize 5-Amino-1MQ to trace how blocking this conversion alters the cellular methyl balance and preserves localized precursor pools
Yet the consequences are unknown Bioavailability: there are four specific metabolic steps necessary to convert cyanocobalamin into one of the coenzyme forms, which is a clear metabolic disadvantage (3) Utilisation problems: certain hereditary diseases, as well as metabolic disorders, prevent the conversion of cyanocoalamin into the active B12 forms (4) Steals methyl groups: cyanocobalamin requires a methyl group to convert into methylcobalamin, which it takes from the important amino acid S-adenosylmethionine (SAM)
References [edit] "Inorganic Cyanide as Protecting Group in the Stereospecific Reconstitution of Vitamin B 12 from an Artificial Green Secocorrinoid" (PDF)
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