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The anti-hypertensive effect of GLP-1R agonists has been observed with liraglutide that is able to mediate atrial natriuretic peptide secretion from atrial cardiomyocytes, thus lowering systolic and diastolic blood pressure increased by angiotensin II (Kim et al., 2013)
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Most currently available GLP-1 medications are given through subcutaneous injection
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