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For context, Ozempic in the US runs $900 to $1,100 per month without insurance
These formulations address the core challenges of salivary washout, limited residence time, and epithelial permeability that currently limit sublingual peptide absorption
The National Drug Formulary describes a starting dose of 2.5 mg once weekly, followed by gradual dose escalation when appropriate
Animal studies have demonstrated that continuous administration of IGF-1 can prevent cartilage degradation and promote repair, highlighting its potential as a treatment for osteoarthritis (Wen et al., 2021)
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