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Both types of regulation involve the transcriptional factor Yap1p ( Bioinformatic analysis of transcription factor binding sites (TFBS) localised in the promoter region of GSH1 of S.bacillaris revealed two proteins that can potentially be involved in its transcriptional regulation (Azf1p and Tec1p), while five other proteins (Aft2p, Aft1p, Gis1p, Pho4p and Rlm1p) are putatively involved in the regulation of GSH2

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To do this, we used a previous program to study whole-body acetaminophen metabolism [10]