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For obesity management, NICE technology appraisals recommend liraglutide 3.0 mg or semaglutide 2.4 mg only as part of a specialist weight management service for adults with a BMI of 35 kg/m (or 32.5 kg/m for people from certain ethnic backgrounds) and at least one weight-related comorbidity
By week four, most patients advance to 0.5 mg, continuing the weekly cadence
These can include nausea, acid reflux, constipation or diarrhea, and rarely, a type of thyroid cancer called medullary thyroid cancer
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