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Wegovy must be used for the following FDA-approved indications to get Aetna coverage: Use the medication along with a reduced-calorie diet and increased physical activity: To lower the risk of serious cardiovascular events (such as death from cardiovascular disease, non-fatal heart attack, or non-fatal stroke) in adults who have existing heart disease and are either overweight or obese

This highlights the likely complex interplay of genetics, hormones, biology and metabolism that all likely play a role in governing body weight in addition to our physical activity and diet

If you're shopping for a Phase 3-supported alternative to tirzepatide, retatrutide is the strongest candidate