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Oxidative stress-induced diseases via the ASK1 signaling pathway

Haematopoiesis (Blood Formation): B12 is crucial, alongside folic acid, for the synthesis of DNA and the proper maturation of red blood cells

Funding This work was supported by the National Natural Science Foundation of China (8247143079), The Discipline Construction Project of Hunan University of Chinese Medicine (Z2023JBGS05), the Key Project of Education Bureau of Hunan Province (23A0293), the Hunan Province Science and Technology Innovation Leading Talent Project (2021RC4034), the Key Project at Central Government Level: the ability establishment of sustainable use for valuable Chinese medicine resources (2060302)

What sets Stage 3 apart clinically is that even small stressors may trigger an adrenal crash, and each crash may take longer to recover from than the last, without fully returning the body to its previous baseline