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Rheumatoid arthritis For the past few decades, the parallel relationship between lactate and rheumatoid arthritis (RA) has been recognized owing to lactate enrichment in synovial cells, endowing it with the trait of being a reliable indicator for differentiating RA [17]

Adv Clin Exp Med 31(11):12651274

Extrapolating mecasermin data to IGF-1 LR3 is problematic because the pharmacokinetics and tissue exposure profiles differ significantly due to the binding protein modifications