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Hufeldt, M
Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics
Its approach of blocking the NNMT enzyme allows the body to shift from storing fat to burning it, all while boosting NAD+ levels for cellular energy and activating the SIRT1 gene for anti-aging effects
Because it modulates a methylation and NAD+ pathway, interactions with other metabolically active compounds cannot be ruled out and have not been characterised in humans
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