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Decisions should be based on the patients metabolic health, cardiovascular risk, weight history, medications, family history, and overall clinical picture

The observation that the insulinotropic actions of GLP-1 are reduced in type 2 diabetes mellitus (T2DM) led to the development of incretin-based therapies GLP-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of hyperglycaemia in these patients

The GLP-1 hormone also impacts areas of the brain that process how hungry a person is

Women with obesity are more likely to experience anovulation (absence of ovulation), irregular menstrual cycles, and polycystic ovary syndrome (PCOS), a common endocrine disorder affecting fertility