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McBean, G.J., et al., Thiol redox homeostasis in neurodegenerative disease
Some people may experience mild side effects when increasing their L-carnitine intake, especially with long-term use
A primary mechanism is the disruption of the epithelial barrier via its virulence adhesin FadA, which binds to E-cadherin on host cells, leading to the activation of the NF-B pathway and the upregulation of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6 (Li et al., 2021
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