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Dont take Contrave if you are : Pregnant, planning to become pregnant, or breastfeeding Undergoing alcohol or sedative withdrawal, or have suddenly stopped use of alcohol, benzodiazepines, barbiturates, or antiepileptic drugs Taking opioids or medications to treat opioid dependence Taking another medication that contains bupropion, such as Wellbutrin Taking an MAOI (monoamine oxidase inhibitor) currently or in the last 14 days Allergic to naltrexone, bupropion, or any ingredient in the medication You also shouldnt take Contrave if you have any of the following conditions: Uncontrolled high blood pressure (hypertension) Seizure disorder or a history of seizures Anorexia nervosa or bulimia Severe liver or kidney disease Who shouldnt take Wegovy

Your second line of defense is your liver

10.1016/j.cell.2014.03.011 27 BellancaC

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