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A Metabolic Win with Reproductive Perks As interest in these medications grows, many men have concerns about how GLP-1 therapy might impact their fertility, hormone levels, and sexual health

Reference: Taipale H, Taylor M, Lhteenvuo M et al., Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study, The Lancet Psychiatry

Treatments that augment insulin-stimulated MBF also improve insulin sensitivity and these include: metformin [33], 5-aminoimidazole-4-carboxamide-1--D-ribofuranoside (activator of AMP-activated protein kinase) [34], glucagon-like peptide-1 [35], sodium salicylate [36] and exercise training [37, 38]

Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study