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Key Functional Differences: NAD+: For energy production and DNA repair Glutathione: For antioxidant defense (fighting free radicals and regenerating other antioxidants) and detoxification NAD vs Glutathione: How They Work Should You Choose NAD or Glutathione
Both approaches produce good results
These in vitro results have been further validated in murine models of malaria infection and rheumatoid arthritis, where G6PD-d or inhibition leads to less severe proinflammatory responses to stimulation marked by reduced Th1 and Th17 differentiation, decreased proatherogenic cytokines IL-1, IL-6, IL-12, and TNF, and no impact on IL-10 and TGF (classically Treg-derived) 120,121,122,123,124
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