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It is primarily researched for its interaction with nicotinamide N-methyltransferase (NNMT), an enzyme linked to energy balance and adipose tissue function
Niacinamide may support cellular energy metabolism during the metabolic changes GLP-1 therapy induces
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"It would not establish an approved indication, standardized dose, demonstrated efficacy, or an FDA-reviewed safety profile." For FDA approval, the peptides would need to undergo large and rigorous randomized controlled trials to validate their efficacy and safety
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