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Faster heart rate More in higher-dose groups Average heart rate rose more in the higher-dose groups, peaked around week 24, then came back down
Both build their effect gradually as you titrate up through the dose schedule, so neither is an overnight switch
The percentage of time spent on diagonal paws decreases between 3 and 6 months for both vehicle and liraglutide dosed animals but there was no significant difference between the groups
As indicated earlier, peptide inhibition of DPP-IV may therefore involve multiple mechanisms of action
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