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Melanotan 2 at a Glance Melanotan 2 (alpha-MSH Analog) Type: Synthetic analog of alpha-MSH | Primary Target: MC1R (melanocortin 1 receptor) | Secondary Targets: MC3R, MC4R, MC5R | Primary Effect: Skin darkening (eumelanin production) | Secondary Effects: Sexual arousal, appetite suppression | Route: Subcutaneous injection | FDA Status: Not approved | Related: PT-141 (bremelanotide), derived from MT-2 research MT-2 was originally developed at the University of Arizona in the 1990s as a potential preventive treatment for skin cancer