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GoF receptors are often characterised by a greater propensity for G protein versus -arrestin recruitment and signalling, slower rate of receptor internalisation and rapid recycling back to the plasma membrane, with these characteristics being independent of their surface expression levels (Liu et al., 2022)
Analytical and preclinical laboratory work uses much lower working concentrations, with each assay receptor binding, HPLC characterization, mass spectrometry confirmation, and stability studies having its own working range
"Effect of epitalon on interleukin-1 signal transduction and the reaction of thymocyte blast transformation under stress." Bulletin of Experimental Biology and Medicine
