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doi: 10.1038/s41467-024-49186-0 60 KapoorMMartel-PelletierJLajeunesseDPelletierJPFahmiH
In a phase 2 clinical trial for obesity, 26 weeks of efinopegdutide (doses 5 to 10mg) resulted in up to 11.8% WL in people with obesity (without diabetes) compared to 7.5% WL with liraglutide 3 mg and 1.8% WL with placebo [77, 78]
Why L-Tartrate
In the context of Alzheimer's disease, reduced lactylation of tau at K677 inhibits ferroptosis by disrupting ferritinophagy, resulting in dysregulated iron metabolism and increased resistance to cell death (119)
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