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Niacinamide: A form of vitamin B3, niacinamide enhances skin hydration, reduces inflammation, and minimizes the appearance of fine lines and wrinkles

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Specifically, women treated with GLP-1 RAs may experience greater glycaemic control and weight-reduction benefits, as well as a higher incidence of gastrointestinal adverse events, compared with men [59]

However, no direct head-to-head comparisons have been conducted, and the 48-week timeframe in the retatrutide trial is shorter than the 6872 week endpoints used in the semaglutide and tirzepatide phase 3 trials, making direct numerical comparison imprecise