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A registry check of ClinicalTrials.gov reveals no large, completed, published trials establishing a human safety profile
OASIS trials: establishing effective doses Phase 2 OASIS 1 findings: Tested multiple dose levels: 0.3mg, 0.6mg, 1.2mg, 2.4mg, 4.5mg weekly Duration: 26 weeks Primary endpoint: Weight loss at each dose Dose-response results: 0.3mg weekly: ~4% body weight loss 0.6mg weekly: ~6% body weight loss 1.2mg weekly: ~8% body weight loss 2.4mg weekly: ~10% body weight loss 4.5mg weekly: ~12% body weight loss Key insight: Clear dose-response relationship
This is the reason why you cant overdose on B12, and its also the reason why you want to inject on a daily basis
Repeated freeze-thaw cycles destroy peptides through ice crystal formation that physically tears apart molecular structures
