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Both formulations are administered as intramuscular injections, usually weekly, as part of a medically-supervised weight loss protocol that includes caloric restriction and, increasingly, GLP-1 receptor agonist therapy like semaglutide or tirzepatide

Those prescribed GLP-1 medications for weight management through NHS specialist services (typically individuals with BMI 35 kg/m or 30 kg/m with comorbidities, according to NICE criteria) may target a larger calorie deficit than those using these medications primarily for glycaemic control with modest weight management