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According to recent data, the global prevalence of diabetes reached 529 million individuals by 2021, with type 2 diabetes mellitus (T2DM) accounting for 96.0% of all cases, particularly reflecting its high prevalence among older adults ( In this context, glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a novel class of antidiabetic and anti-obesity agents, have gained widespread recognition for their safety, efficacy, and metabolic benefits in managing T2DM and obesity
The winning molecule, called liraglutide, entered clinical testing in 2000 as an injectable drug to treat diabetes, and would eventually be approved by the FDA, as Victoza in 2010
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