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It also activates proteins known as sirtuins that regulate DNA repair and cellular longevity
Medical Reasons to Take a Planned Break from Semaglutide Legitimate reasons for a temporary pause include severe nausea unresponsive to dose adjustment, planned surgery requiring medication pauses, acute illness, or pregnancy planning (as semaglutide safety in pregnancy is not established)
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15 In the SURPASS-1 study, tirzepatide monotherapy at increasing doses of 5, 10, and 15 mg resulted in significant weight loss of 7, 7.8, and 9.5 kg, respectively, at week 40 in patients with T2DM, compared with a 0.7 kg decrease with placebo
