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La eventual accin benfica de la liraglutida en el riesgo cardiovascular en pacientes con DM2 est siendo investigado en el estudio LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results)64
While retatrutide shows lower potency at human GLP-1 and glucagon receptors compared to natural ligands, it demonstrates higher potency at the GIP receptor by a factor of nearly 9x, and the combined effect is what drives the superior outcomes
adults could be considered obese by 2030 the need for safe, effective and accessible weight management care continues to grow
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