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European Journal of Nutrition, 54 (2), 251263

C.SiddensL

doi: 10.2337/db11-0979 18 rskovCHolstJJNielsenOV

Ultimately, this FOXO4-DRI-mediated mechanism selectively eliminates senescent endothelial cells, which in turn attenuates vascular inflammation and improves endothelial-dependent vasodilation, conferring a significant protective effect on vascular function