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Treatment of Gclc L-KO with GSH-ee reduced the observed increased Nrf2 target gene expression to basal levels in a dose-dependent manner (Fig
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Patients with conditions like chronic fatigue syndrome or fibromyalgia might be interested in exploring the use of glutathione in their management plans, in conjunction with their healthcare provider's guidance It is important, however, for both patients and prescribers to note that while there is anecdotal and initial scientific support for these uses, the established evidence is limited, and further research is required to fully understand the efficacy and safety of glutathione in these contexts
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