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Unlike small-molecule drugs that rely on cytochrome P450 enzymes for hepatic biotransformation, peptides such as BPC-157 are degraded by ubiquitous proteases throughout the body [4]
(PubMed) Frei B, Birlouez-Aragon I, Lykkesfeldt J
(3) Persistence adds valuable information
There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision
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