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However, compelling cellular and ex vivo tissue models have indicated a causal role for oxidative stress (OS) in the development of IR [4][11]

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Kitteringham NR, Powell H, Clement YN, Dodd CC, Tettey JN, Pirmohamed M, Smith DA, McLellan LI, Kevin Park B: Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase