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Shi Y, Wang CC, Yang Y, et al
Injecting air into the vial introduces atmospheric oxygen that accelerates glutathione oxidation, converting the active reduced form (GSH) to the inactive oxidized form (GSSG)
In addition, a combination regimen of PARPi and copanlisib (a PI3K inhibitor) was tested in phase I/II trials (NCT03586661 and NCT05295589) in patients with BRCA-mutated, resistant ovarian cancer
A liposome is an oil particle that encapsulates the glutathione helping to protect it from the acids in the stomach
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