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Berberine is a yellow alkaloid compound extracted from several plants such as goldenseal, Oregon grape, and tree turmeric
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Although long-acting glucagon-like peptide-1 (GLP-1) analogues are now in routine use for diabetes and are now being utilised for obesity per se , the need for ever better treatments has driven the development of co-agonists, with the theoretical advantages of improved efficacy by targeting multiple pathways and reduced adverse effects
Allocation decisions can become ethically and operationally sensitive , particularly when patients with chronic glycemic needs compete with new initiations for weight management
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