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Roughly one-third of users who stopped taking GLP1s during the study reverted to their previous spending habits and even ended up with slightly less healthy grocery baskets than before they started, marked by increased spending on candy and chocolatesuggesting that cravings come back stronger

(B) LRs from dHL60 cells were extracted with MNE buffer containing 1% triton X-100 and applied to discontinuous sucrose gradients, as described in Methods

Reactions were quenched by the addition of 2.5 M GuHCl (8 M) and reduced by the addition of 10 mM TCEP (200 mM) for 20 min at 65 C