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Key transcription factors that are downregulated include NeuroD1, which negatively affects the transition of neuronal progenitor cells into post-mitotic neurons and disrupts dentate gyrus development (Pavlinkova & Smolik 2024)
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308,309 These transient adaptive states may subsequently serve as reservoirs from which genetically resistant clones emerge
Belvisi MG, Stretton CD, Barnes PJ
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