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[27] During clinical trials, oxymetazoline topical cream was associated with application site reactions, including contact dermatitis (2% to 3%), pruritus (1% to 2%), erythema (1% to 2%), and pain (1% to 2%)

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Comparing the effective dose of ASSOE to the equivalent irradiation groups 2, 3, and 4, the concentrations of CD4 and CD8 (pg/ml) were considerably increased to 110.74 and 301.51 in group 5, 85.47 and 396.22 in group 6, and 93.12 and 244.94 pg/ml in group 7