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Other statin drugs, such as rosuvastatin and fluvastatin, can increase GSH and/or GPX in the myocardium to alleviate ISO-mediated myocardial injury [230, 231]

However, once ROS levels exceed the buffering capacity on response to multiple stimuli, a series of adaptive responses that are combined with inflammatory responses followed by intracellular damage are activated, which further lead to progressive mitochondrial dysfunction and cell death [25]

And that number could experience even more growth this year

And I think we struggle a lot with, I think the medicine just thinks that being healthy is just not having a disease