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Both classes of enzyme are involved in a wide range of red-ox reactions and includes the same critical thiamine-dependent enzymes described above, the pyruvate dehydrogenase complex (PDHc), 2-oxoglutarate (-ketoglutarate) dehydrogenase (OGDH), and branched-chain -ketoacid dehydrogenase (BCKD)
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Experimental observations indicate stimulation of fibroblast proliferation, collagen production, and tissue remodeling responses following injury or stress
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