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In the group already struggling with addiction, there were 50% fewer deaths due to substance use among those taking GLP-1 drugs compared with those who were not
However, oral formulations of B12, methionine, inositol, and choline are widely available, less expensive, and equally evidence-supported for addressing documented deficiencies
Chinese Medical Journal
As the field develops, direct measurement of circulating MOTS-c may become a useful biomarker for guiding dose adjustments, similar to how IGF-1 is used to monitor growth hormone or testosterone levels guide TRT dosing
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