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Desrosiers TA, Siega-Riz AM, Mosley BS, Meyer RE, National Birth Defects Prevention S

GSDME is highly expressed in normal colon epithelium, and radiation induces GSDME-mediated pyroptotic cell death, resulting in the release of the proinflammatory cytokines IL1, IL6, TNF, and HMGB1, which recruit and activate NK cells, leading to radiotherapy-associated colitis 49

If youre considering Mounjaro or metformin for weight loss, clinical trials show some clear differences between the two

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