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While the role of adipose tissue as a central source of energy has been recognized for centuries, in the past decade, it has become increasingly clear that adipose tissue also displays characteristics of an endocrine organ releasing a number of adipose tissue-specific factors, known as adipokines

HSS journal : the musculoskeletal journal of Hospital for Special Surgery , 21 (4), 15563316251355551

Pharmacological inhibition of CPT1A results in impaired cancer cell proliferation in acute myeloid leukemia and intensive cytotoxicity in Burkitts lymphoma 23,32

It also notes B vitamin supplementation in excess can occasionally cause side effects, and suggests baseline biomarkers help show whether added lipotropic support addresses a real need or is simply redundant