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Synthetic biology-based approaches, such as SYNB1891, a live microbial vector delivering STING agonists, have been evaluated for intratumoral immune activation in metastatic tumors (NCT04167137)
doi: 10.1155/2013/168039 54 TiongYLNgKYKohRYPonnuduraiGChyeSM
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Nat Med (2013) 19:111423
