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One recent study of over 10,000 adults using GLP-1s looked at how often they experienced GI side effects across semaglutide (Ozempic and Wegovy ), liraglutide (Victoza or Saxenda ), dulaglutide (Trulicity ), and exenatide (Byetta or Bydureon )
Over two months, I evaluated taste, solubility, ingredient quality and how each product felt during and after use
It is known that gut microbes can metabolize EGCG into fission products that are more bioavailable and easier to pass through the BBB to exert neuroprotective effects (214)
We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs
