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Discussion While GLP-1 RAs are powerful anti-obesity medications (AOMs), they do raise some serious concerns most notably, up to 40% of the profound weight loss induced by these agents can be due to loss of lean mass 3,4,5 and prior studies have shown that a significant portion of this lean mass is muscle 33,34,35

Cognitive studies in patients with TBI and hydrocephalus have also identified impairments in problem-solving [7], executive function [8], short-term and working memory [9, 10]

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To qualify, patients need to have a BMI of 30, or a BMI of 27 with a weight-related health condition (such as pre-diabetes or heart disease)