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It identifies freezing, repeated temperature swings, and storage at room temperature as the three things that accelerate degradation, with consistency of refrigeration described as the primary determinant of how long a preparation stays usable
doi: 10.1124/pr.108.000604 3 GrrizJLSolerMJNavarro-GonzlezJFGarca-CarroCPuchadesMJD'MarcoLet al
All 4 trials described random sequence generation and allocation concealment, reported clinically relevant outcome measures, and undertook sample size calculations [30], [32], [34], [36]
The warning triggers an inflammatory response to fight the threat, but the excess inflammation that results becomes life-threatening in itself
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