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Collectively, these data highlight an important role of ETC and mitochondrial lipid redox signaling in GPX4-dependent ferroptosis in AML cells and anticipate that targeting both pathways (i.e

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Methionine and cysteine affect glutathione level, glutathione-related enzyme [PMID: 9372907] Laboratory literature summary: Methionine and cysteine affect glutathione level, glutathione-related enzyme activities and the expression of glutathione S-transferase