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A subsequent study identified the compound N-(4-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)phenyl)acetamide as a notable SARM1 inhibitor, which demonstrated significant efficacy in a mouse model of CIPN (Fig
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Efficacy outcomes were measured through glycosylated hemoglobin (HbA1c) levels, along with other markers of glycemic control
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