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Pearson SD et al

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Ozempic, however, is narrowly indicated for the treatment of type 2 diabetes, focusing its efficacy on improving blood sugar levels in adults, and is not approved for weight management despite potential weight-reducing side effects that may benefit some patients

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There are even more allosteric interactions in the folate and the methionine cycles, but, for simplicity, we are not showing all of them

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Importantly, the genetic variants did not appear to affect responses to several other common diabetes medications, including sulfonylureas, metformin, and DPP-4i drugs

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