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The semaglutide group achieved a mean BMI reduction of 16.1% compared with a 0.6% increase in the placebo arm (estimated treatment difference: 16.7 percentage points
Specifically, in contrast to normal individuals, patients with MASH show upregulated expression of senescence- and exhaustion-related genes in hepatic CD4+ and CD8+ T cells, along with increased expression of IL-2, IL-15 and IL-18 in these cells
Amodio, N
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